Zithromax mode of action

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  1. Diks_SS New Member

    Zithromax mode of action


    Generic Name: Azithromycin (multiple manufacturers) Common Brand Name: Zithromax (Pfizer — U. S.) Popularity: 11th most commonly prescribed drug between 2002 — 2007 (U. S.) Class: Macrolide antibiotic Treatment Uses — For treatment of bacterial infections. Azithromycin has distinct advantages over earlier macrolides such as erythromycin that include better tolerance, better tissue penetration and more favorable pharmacokinetics. Because azithromycin can be dosed once daily, it improves patient compliance — a leading cause of antibiotic failures. Macrolides act primarily against streptococci and staphylococci, and are often used to treat these bugs in patients intolerant of penicillins. The therapeutic uses for azithromycin are broad and continually changing. Each film-coated tablet contains 250 mg azithromycin (as azithromycin monohydrate) Excipient(s) with known effect: Each film-coated tablet contains 6.84 mg lactose (as lactose monohydrate) and 0.57 mg (0.025 mmol) sodium. Azithromycin is indicated for the treatment of the following infections, when caused by microorganisms sensitive to azithromycin (see section 4.4 and 5.1): - acute bacterial sinusitis (adequately diagnosed) - acute bacterial otitis media (adequately diagnosed) - pharyngitis/tonsillitis - acute exacerbation of chronic bronchitis (adequately diagnosed) - mild to moderately severe community-acquired pneumonia - skin and soft tissue infections - uncomplicated Chlamydia trachomatis urethritis and cervicitis Consideration should be given to official guidance on the appropriate use of antibacterial agents. Posology Adults In uncomplicated Chlamydia trachomatis urethritis and cervicitis the dosage is 1,000 mg as a single oral dose. For all other indications the dose is 1,500 mg, to be administered as 500 mg per day for three consecutive days. Older people The same dose range as in younger patients may be used in the elderly. Children Azithromycin film-coated tablets should only be administered to children weighing more than 45 kg when normal adult dose should be used. For children under 45 kg other pharmaceutical forms of azithromycin, e.g. Patients with renal impairment: No dose adjustment is necessary in patients with mild to moderate renal impairment (GFR 10-80 ml/min) (see section 4.4). Patients with hepatic impairment: A dose adjustment is not necessary for patients with mild to moderately impaired liver function (see section 4.4).

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    Zithromax Azithromycin belongs to the family of medications known as macrolide. or street drugs can affect the action of many medications, you should let your. Zithromax, Azithrocin, others Synonyms 9-deoxy-9α-aza-9α-methyl-9α-homoerythromycin A. Azithromycin is an antibiotic useful for the treatment of a number of bacterial infections. Mechanism of action. Azithromycin prevents bacteria from growing by interfering with their protein synthesis. Zithromax is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated

    Azithromycin tablets can be applied for the treatment of the following infections, when caused by microorganisms sensitive to azithromycin (see sections 4.4 and 5.1): - acute bacterial sinusitis (adequately diagnosed) - acute bacterial otitis media (adequately diagnosed) - pharyngitis, tonsillitis - acute exacerbation of chronic bronchitis (adequately diagnosed) - mild to moderately severe community acquired pneumonia - skin and soft tissue infections - uncomplicated Chlamydia trachomatis urethritis and cervicitis Considerations should be given to official guidance on the appropriate use of antibacterial agents. Adults In uncomplicated Chlamydia trachomatis urethritis and cervicitis the dose is 1000 mg as a single oral dose. For all other indications the dose is 1500 mg, to be administered as 500 mg per day for three consecutive days. As an alternative the same total dose (1500 mg) can also be administered over a period of five days with 500 mg on the first day and 250 mg on the second to the fifth day. Elderly people The same dose as in adult patients is used for elderly people. Since older people can be patients with ongoing proarrhythmic conditions a particular caution is recommended due to the risk of developing cardiac arrhythmia and torsades de pointes (see section 4.4). Paediatric population Azithromycin tablets should only be administered to children weighing more than 45 kg when normal adult dose should be used. Azithromycin is indicated for the treatment of the following infections when known or likely to be due to one or more susceptible microorganisms (see section 5.1): - bronchitis - community-acquired pneumonia - sinusitis - pharyngitis/tonsillitis (see section 4.4 regarding streptococcal infections) - otitis media - skin and soft tissue infections - uncomplicated genital infections due to Chlamydia trachomatis and Neisseria gonorrhoeae. Considerations should be given to official guidance regarding the appropriate use of antibacterial agents. Zithromax capsules should be given as a single daily dose. In common with many other antibiotics Zithromax Capsules should be taken at least 1 hour before or 2 hours after food. Children over 45 kg body weight and adults, including elderly patients: The total dose of azithromycin is 1500 mg which should be given over three days (500 mg once daily). In uncomplicated genital infections due to Chlamydia trachomatis, the dose is 1000 mg as a single oral dose. For susceptible Neisseria gonorrhoeae the recommended dose is 1000 mg or 2000 mg of azithromycin in combination with 250 mg or 500 mg ceftriaxone according to local clinical treatment guidelines.

    Zithromax mode of action

    Zithromax Azithromycin Side Effects, Interactions., Azithromycin - Wikipedia

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  6. Pharmacodynamics Mode of Action Azithromycin is the first of a subclass of macrolide antibiotics, known as azalides, and is chemically different from erythromycin. Chemically it is derived by insertion of a nitrogen atom into the lactone ring of erythromycin A.

    • Zithromax Mechanism of Action Philippines.
    • Zithromax - FDA prescribing information, side effects and uses.
    • Zithromax 250 Capsules - Summary of Product Characteristics SmPC..

    Azithromycin is a macrolide antibiotic with well-described anti-inflammatory properties which can be attributed, at least partially, to its action on macrophages. Mechanism of action. Azithromycin is a bacteriostatic drug acts by inhibiting protein synthesis. It binds reversibly to 50S ribosomal subunits of sensitive microorganism. Azithromycin interferes with transpeptidation and translocation thus there is inhibition of protein synthesis and Sep 1, 2016. Azithromycin became one of the best-selling branded antibiotics worldwide. Structural. Macrolides and Their Mode of Action as Anti-Infectives.

     
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    This medicine is not recommended for use in patients with a known history of tendon rupture or tendinitis (a condition in which the tissue connecting muscles to the bones becomes inflamed) due to the increased risk of worsening of the patient's condition. This medicine is not recommended for use in patients with a known history or family history of myasthenia gravis (weakness and rapid fatigue of muscles under voluntary control) due to the increased risk of worsening of the patient's condition. This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects. Use of this medicine will increase the risk of developing tendinitis or tendon rupture during the treatment or several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. Cipro Ciprofloxacin Side Effects, Interactions, Warning, Dosage. Cipro - Uses, Side Effects, Interactions - Drug Side Effects for Older Adults - Next Avenue
     
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  10. Prednisone Oral Route Description and Brand Names - Mayo Clinic Description and Brand Names. Drug information provided by IBM Micromedex. US Brand Name. Deltasone; Prednicot; predniSONE Intensol; Rayos; Sterapred; Sterapred DS

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