It is also used for liver cirrhosis, kidney impairment, nephrotic syndrome, in adjunct therapy for swelling of the brain or lungs where rapid diuresis is required (IV injection), and in the management of severe hypercalcemia in combination with adequate rehydration. Furosemide also can lead to gout caused by hyperuricemia. The tendency, as for all loop diuretics, to cause low serum potassium concentration (hypokalemia) has given rise to combination products, either with potassium or with the potassium-sparing diuretic amiloride (Co-amilofruse). Other electrolyte abnormalities that can result from furosemide use include hyponatremia, hypochloremia, hypomagnesemia, and hypocalcemia. Furosemide, like other loop diuretics, acts by inhibiting the luminal Na-K-Cl cotransporter in the thick ascending limb of the loop of Henle, by binding to the chloride transport channel, thus causing sodium, chloride, and potassium loss in urine. The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative, as well as positive, free water clearance. Because of the large Na Cl absorptive capacity of the loop of Henle, diuresis is not limited by development of acidosis, as it is with the carbonic anhydrase inhibitors. Additionally, furosemide is a noncompetitive subtype-specific blocker of GABA-A receptors. Some of the brand names under which furosemide is marketed include: Aisemide, Apo-Furosemide, Beronald, Desdemin, Discoid, Diural, Diurapid, Dryptal, Durafurid, Edemid, Errolon, Eutensin, Flusapex, Frudix, Frusetic, Frusid, Fulsix, Fuluvamide, Furesis, Furix, Furo-Puren, Furon, Furosedon, Fusid.frusone, Hydro-rapid, Impugan, Katlex, Lasilix, Lasix, Lodix, Lowpston, Macasirool, Mirfat, Nicorol, Odemase, Oedemex, Profemin, Rosemide, Rusyde, Salix, Seguril, Teva-Furosemide, Trofurit, Uremide, and Urex. Furosemide belongs to the class of medications called diuretics. It is used to treat edema (fluid retention) that occurs with congestive heart failure and disorders of the liver, kidney, and lung. It is also used to control mild to moderate high blood pressure. It may be used in combination with other medications to treat more severe high blood pressure. Furosemide works by increasing the amount of urine produced and excreted, and by removing excessive water (edema) from the body. The tablet form begins to work within an hour of being taken and usually lasts for 4 to 6 hours. The injectable form begins to work within ½ hour and lasts approximately 2 hours. Ciprofloxacin vs keflex Viagra indigestion Learn about the potential side effects of furosemide. Includes common and rare side effects information for consumers and healthcare professionals. Furosemide systemic 40 mg 3170 V Furosemide systemic 20 mg M2. Buy Lasix Furosemide online from $0.35 / 40 mg pill. Lasix is prescribed at a dose of 20-50 mg per day. Side effects of the drug may include Medscape - Hypertension-specific dosing for Lasix furosemide, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation. Along with its needed effects, furosemide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Lasix (furosemide)." sanofi-aventis , Bridgewater, NJ. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Check with your doctor immediately if any of the following side effects occur while taking furosemide: Some side effects of furosemide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to furosemide: compounding powder, injectable solution, intravenous solution, oral liquid, oral solution, oral tablet Common (1% to 10%): Hyponatremia, hypochloremia, hypokalemia, blood cholesterol increased, blood uric acid increased, gout Uncommon (0.1% to 1%): Thirst, glucose tolerance decreased Rare (0.01% to 0.1%): Anorexia, serum triglycerides increased Frequency not reported: Hyperglycemia, diabetes mellitus, hyperuricemia, metabolic alkalosis, hypocalcemia, hypomagnesemia, hypovolemia, dehydration, tetany, serum potassium decreased, Pseudo-Bartter syndrome, electrolyte disturbances, serum calcium decreased Common (1% to 10%): Hemoconcentration Uncommon (0.1% to 1%): Thrombocytopenia Rare (0.01% to 0.1%): Eosinophilia, leukopenia, bone marrow depression Very rare (less than 0.01%): Hemolytic anemia, aplastic anemia, agranulocytosis Frequency not reported: Anemia, thrombophilia Uncommon (0.1% to 1%): Pruritus, bullous exanthema, rash, urticaria, purpura, erythema multiforme, exfoliative dermatitis, photosensitivity Rare (less than 0.1%): Lyell's syndrome and Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, drug rash with eosinophilia and systemic symptoms Frequency not reported: Toxic epidermal necrolysis, bullous pemphigoid, sweating Uncommon (0.1% to 1%): Dry mouth, nausea, bowel motility disturbances, vomiting, diarrhea, constipation Rare (less than 0.1%): Gastric distress, acute pancreatitis Frequency not reported: Pancreatitis, oral and gastric irritation, cramping Uncommon (0.1% to 1%): Blood creatinine increased, urea increased Rare (less than 0.1%): Interstitial nephritis, acute renal failure Frequency not reported: Nephrocalcinosis in premature infants, nephrolithiasis in premature infants, GFR decreased, tubulointerstitial nephritis Uncommon (0.1% to 1%): Deafness, fatigue Rare (less than 0.1%): Sensation of pressure in the head, dysacusis, asthenia, fever, febrile conditions, malaise Frequency not reported: Weakness, sudden death, hearing disorders, hearing loss, paradoxical swelling Uncommon (0.1% to 1%): Cardiac arrhythmia Rare (less than 0.1%): Vasculitis Frequency not reported: Systemic vasculitis, necrotizing angiitis, orthostatic hypotension, thrombophlebitis, acute hypotension, circulatory collapse, persistent patent ductus arteriosus during the first few weeks of life in premature infants with respiratory distress syndrome, blood pressure decreased, shock, hypotension, thrombosis, orthostatic blood pressure decreased Rare (0.01% to 0.1%): Paresthesia, vertigo, dizziness, sleepiness, tinnitus, hyperosmolar coma Frequency not reported: Hepatic encephalopathy, headache, fainting and loss of consciousness, drowsiness, lethargy, sweet taste1. Before using this medication, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs. Furosemide is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine. Furosemide treats fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. This medication is also used to treat high blood pressure (hypertension). Furosemide may also be used for purposes not listed in this medication guide. Furosemide can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. 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Furosemide, sold under the brand name Lasix among others, is a medication used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. It may also be used for the treatment of high blood pressure. It can be taken intravenously or by mouth. When taken by mouth, it typically begins working within an hour, while intravenously, it typically begins working within five minutes.